Mologni, Carlo: search on Z-Library

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1

Structural Insights into the ATP Binding Pocket of the Anaplastic Lymphoma Kinase by Site-Directed Mutagenesis, Inhibitor Binding Analysis, and Homology Modeling

Gunby, Rosalind H., Ahmed, Shaheen, Sottocornola, Roberta, Gasser, Marc, Redaelli, Sara, Mologni, Luca, Tartari, Carmen J, Belloni, Valentina, Gambacorti-Passerini, Carlo, Scapozza, Leonardo

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 897 KB

english, 2006

2

Crossing taxonomic and isotopic approaches in charcoal analyses to reveal past climates. New perspectives in Paleobotany from the Paleolithic Neanderthal dwelling-site of La Combette (Vaucluse, France)

Audiard, Benjamin, Thery-Parisot, Isabelle, Blasco, Thierry, Mologni, Carlo, Texier, Pierre-Jean, Battipaglia, Giovanna

Journal:

Review of Palaeobotany and Palynology

Year:

2019

File:

PDF, 1.02 MB

2019

3

Crossing taxonomic and isotopic approaches in charcoal analyses to reveal past climates. New perspectives in Paleobotany from the Paleolithic Neanderthal dwelling-site of La Combette (Vaucluse, France)

Audiard, Benjamin, Thery-Parisot, Isabelle, Blasco, Thierry, Mologni, Carlo, Texier, Pierre-Jean, Battipaglia, Giovanna

Journal:

Review of Palaeobotany and Palynology

Year:

2019

Language:

english

File:

PDF, 1.02 MB

english, 2019

4

A rapid method for the purification of wild-type and V804M mutant ret catalytic domain: A tool to study thyroid cancer

Elisa Sala, Luca Mologni, Sara Cazzaniga, Elena Papinutto, Carlo Gambacorti-Passerini

Journal:

International Journal of Biological Macromolecules

Year:

2006

Language:

english

File:

PDF, 322 KB

english, 2006

5

The Novel PIM1 Inhibitor NMS-P645 Reverses PIM1-Dependent Effects on TMPRSS2/ERG Positive Prostate Cancer Cells And Shows Anti-Proliferative Activity in Combination with PI3K Inhibition

Mologni, Luca, Magistroni, Vera, Casuscelli, Francesco, Montemartini, Marisa, Gambacorti-Passerini, Carlo

Journal:

Journal of Cancer

Year:

2017

Language:

english

File:

PDF, 832 KB

english, 2017

6

Inhibitors of the RET tyrosine kinase based on a 2-(alkylsulfanyl)-4-(3-thienyl)nicotinonitrile scaffold

Wiebke Brandt, Luca Mologni, Lutz Preu, Thomas Lemcke, Carlo Gambacorti-Passerini, Conrad Kunick

Journal:

European Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 665 KB

english, 2010

7

Synthesis, structure–activity relationship and crystallographic studies of 3-substituted indolin-2-one RET inhibitors

Luca Mologni, Roberta Rostagno, Stefania Brussolo, Phillip P. Knowles, Svend Kjaer, Judith Murray-Rust, Enrico Rosso, Alfonso Zambon, Leonardo Scapozza, Neil Q. McDonald, Vittorio Lucchini, Carlo Gamb

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 2.61 MB

english, 2010

8

Sphingosine kinase 1 overexpression is regulated by signaling through PI3K, AKT2, and mTOR in imatinib-resistant chronic myeloid leukemia cells

Gabriella Marfe, Carla Di Stefano, Alessandra Gambacurta, Tiziana Ottone, Valentina Martini, Elisabetta Abruzzese, Luca Mologni, Paola Sinibaldi-Salimei, Paolo de Fabritis, Carlo Gambacorti-Passerini,

Journal:

Experimental Hematology

Year:

2011

Language:

english

File:

PDF, 1.80 MB

english, 2011

9

Inhibition of the ABL Kinase Activity Blocks the Proliferation of BCR/ABL+Leukemic Cells and Induces Apoptosis

Carlo Gambacorti-Passerini, Philipp le Coutre, Luca Mologni, Mirco Fanelli, Carla Bertazzoli, Edoardo Marchesi, Massimo Di Nicola, Andrea Biondi, Gian Marco Corneo, Daniela Belotti, Enrico Pogliani, N

Journal:

Blood Cells, Molecules, and Diseases

Year:

1997

Language:

english

File:

PDF, 239 KB

english, 1997

10

Bcr-Abl stabilizes β-catenin in chronic myeloid leukemia through its tyrosine phosphorylation

Coluccia, Addolorata Maria Luce, Vacca, Angelo, Duñach, Mireia, Mologni, Luca, Redaelli, Sara, Bustos, Victor H, Benati, Daniela, Pinna, Lorenzo A, Gambacorti-Passerini, Carlo

Journal:

The EMBO Journal

Year:

2007

Language:

english

File:

PDF, 541 KB

english, 2007

11

Expression, purification, and inhibition of human RET tyrosine kinase

Luca Mologni, Elisa Sala, Barbara Riva, Luca Cesaro, Sara Cazzaniga, Sara Redaelli, Oriano Marin, Nicola Pasquato, Arianna Donella-Deana, Carlo Gambacorti-Passerini

Journal:

Protein Expression and Purification

Year:

2005

Language:

english

File:

PDF, 363 KB

english, 2005

12

Three novel patient-derived BCR/ABL mutants show different sensitivity to second and third generation tyrosine kinase inhibitors

Redaelli, Sara, Mologni, Luca, Rostagno, Roberta, Piazza, Rocco, Magistroni, Vera, Ceccon, Monica, Viltadi, Michela, Flynn, Daniel, Gambacorti-Passerini, Carlo

Journal:

American Journal of Hematology

Year:

2012

Language:

english

File:

PDF, 199 KB

english, 2012

13

Oncogenic Fusion Tyrosine Kinases as Molecular Targets for Anti-Cancer Therapy

Gunby, Rosalind, Sala, Elisa, Tartari, Carmen, Puttini, Miriam, Gambacorti-Passerini, Carlo, Mologni, Luca

Journal:

Anti-Cancer Agents in Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 429 KB

english, 2007

14

9000 years of human lakeside adaptation in the Ethiopian Afar: Fisher-foragers and the first pastoralists in the Lake Abhe basin during the African Humid Period

Khalidi, Lamya, Mologni, Carlo, MÃ©nard, ClÃ©ment, Coudert, Lucie, Gabriele, Marzia, Davtian, Gourguen, Cauliez, Jessie, Lesur, JosÃ©phine, Bruxelles, Laurent, Chesnaux, LorÃ¨ne, Redae, Blade Engda, H

Journal:

Quaternary Science Reviews

Year:

2020

File:

PDF, 8.56 MB

2020

15

In Vitro Transcriptional and Translational Block of the bcl-2 Gene Operated by Peptide Nucleic Acid

Luca Mologni, Peter E. Nielsen, Carlo Gambacorti-Passerini

Journal:

Biochemical and Biophysical Research Communications

Year:

1999

Language:

english

File:

PDF, 209 KB

english, 1999

16

ChemInform Abstract: Inhibitors of the RET Tyrosine Kinase Based on a 2-(Alkylsulfanyl)-4-(3-thienyl) Nicotinonitrile Scaffold.

Wiebke Brandt, Luca Mologni, Lutz Preu, Thomas Lemcke, Carlo Gambacorti-Passerini, Conrad Kunick

Journal:

Year:

2010

Language:

english

File:

PDF, 38 KB

english, 2010

17

Activity of second-generation ALK inhibitors against crizotinib-resistant mutants in an NPM-ALK model compared to EML4-ALK

Fontana, Diletta, Ceccon, Monica, Gambacorti-Passerini, Carlo, Mologni, Luca

Journal:

Cancer Medicine

Year:

2015

Language:

english

File:

PDF, 1.10 MB

english, 2015

18

Induction of resistance to the Abelson inhibitor STI571 in human leukemic cells through gene amplification

le Coutre, Philipp, Tassi, Elena, Varella-Garcia, Marileila, Barni, Rossella, Mologni, Luca, Cabrita, GoncÌ§alo, Marchesi, Edoardo, Supino, Rosanna, Gambacorti-Passerini, Carlo

Journal:

Year:

2000

File:

PDF, 280 KB

2000

19

New developments in the treatment of ALK-driven malignancies

Mologni, Luca, Gambacorti-Passerini, Carlo

Journal:

Clinical Investigation

Year:

2012

Language:

english

File:

PDF, 836 KB

english, 2012

20

Valproic acid enhances bosutinib cytotoxicity in colon cancer cells

Luca Mologni, Loredana Cleris, Vera Magistroni, Rocco Piazza, Frank Boschelli, Franca Formelli, Carlo Gambacorti-Passerini

Journal:

International Journal of Cancer

Year:

2009

Language:

english

File:

PDF, 401 KB

english, 2009

21

PNAs as novel cancer therapeutics

Luca Mologni, Carlo Gambacorti-Passerini

Journal:

International Journal of Peptide Research and Therapeutics

Year:

2005

Language:

english

File:

PDF, 210 KB

english, 2005

22

PNAs as novel cancer therapeutics

Luca Mologni, Carlo Gambacorti-Passerini

Journal:

International Journal of Peptide Research and Therapeutics

Year:

2003

Language:

english

File:

PDF, 1.26 MB

english, 2003

23

Ponatinib is a potent inhibitor of wild-type and drug-resistant gatekeeper mutant RET kinase

Mologni, Luca, Redaelli, Sara, Morandi, Andrea, Plaza-Menacho, Ivan, Gambacorti-Passerini, Carlo

Journal:

Molecular and Cellular Endocrinology

Year:

2013

Language:

english

File:

PDF, 811 KB

english, 2013

24

Unique Substrate Specificity of Anaplastic Lymphoma Kinase (ALK): Development of Phosphoacceptor Peptides for the Assay of ALK Activity †

Donella-Deana, Arianna, Marin, Oriano, Cesaro, Luca, Gunby, Rosalind H., Ferrarese, Anna, Coluccia, Addolorata M. L., Tartari, Carmen J., Mologni, Luca, Scapozza, Leonardo, Gambacorti-Passerini, Carlo

Journal:

Year:

2005

Language:

english

File:

PDF, 192 KB

english, 2005

25

Design, Synthesis, and Biological Activity of Urea Derivatives as Anaplastic Lymphoma Kinase Inhibitors

Gustav Boije af Gennäs, Dr. Luca Mologni, Dr. Shaheen Ahmed, Dr. Mohanathas Rajaratnam, Prof. Oriano Marin, Niko Lindholm, Michela Viltadi, Prof. Carlo Gambacorti-Passerini, Prof. Leonardo Scapozza, P

Journal:

Year:

2011

Language:

english

File:

PDF, 1.42 MB

english, 2011

26

PNAs as novel cancer therapeutics

Luca Mologni, Carlo Gambacorti-Passerini

Journal:

International Journal of Peptide Research and Therapeutics

Year:

2003

Language:

english

File:

PDF, 202 KB

english, 2003

27

Somatic mutations identified at diagnosis by exome sequencing can predict response to imatinib in chronic phase CML patients

Mologni, Luca, Piazza, Rocco, Khandelwal, Praveen, Pirola, Alessandra, Gambacorti-Passerini, Carlo

Journal:

American Journal of Hematology

Year:

2017

Language:

english

File:

PDF, 947 KB

english, 2017

28

Mitochondrial Hyperactivation and Enhanced ROS Production are Involved in Toxicity Induced by Oncogenic Kinases Over-Signaling

Ceccon, Monica, Mauri, Mario, Massimino, Luca, Giudici, Giovanni, Piazza, Rocco, Gambacorti-Passerini, Carlo, Mologni, Luca

Journal:

Year:

2018

Language:

english

File:

PDF, 2.08 MB

english, 2018

29

An Imatinib–non‐responsive patient with an ABL Leu387Trp mutation achieves cytogenetic and molecular response under bosutinib: Case report and biological characterization

Crespiatico, Ilaria, Bossi, Elisa, Brioschi, Filippo, Piazza, Rocco, Mologni, Luca, Gambacorti‐Passerini, Carlo

Journal:

Clinical Case Reports

Year:

2019

File:

PDF, 358 KB

2019

30

Synthesis and biological evaluation of benzo[4,5]imidazo[1,2-c]pyrimidine and benzo[4,5]imidazo[1,2-a]pyrazine derivatives as anaplastic lymphoma kinase inhibitors

Tardy, Sébastien, Orsato, Alexandre, Mologni, Luca, Bisson, William H., Donadoni, Carla, Gambacorti-Passerini, Carlo, Scapozza, Leonardo, Gueyrard, David, Goekjian, Peter G.

Journal:

Bioorganic & Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 3.30 MB

english, 2014

31

Tumor Resistance against ALK Targeted Therapy-Where It Comes From and Where It Goes

Sharma, Geeta, Mota, Ines, Mologni, Luca, Patrucco, Enrico, Gambacorti-Passerini, Carlo, Chiarle, Roberto

Journal:

Year:

2018

Language:

english

File:

PDF, 1.66 MB

english, 2018

32

SAE Technical Paper Series [SAE International SAE Brasil 2010 Congress and Exhibit - (OCT. 05, 2010)] SAE Technical Paper Series - Accelerating the Vehicle Development Process by Employing EMI and EMC Numerical Analysis Assisted by High Performance Computing

Mologni, Juliano Fujioka, Bonadiman, Mateus, Guimaraes, Antonio Carlos, Alvarenga, Leonardo, Colin, Arnaud, Paulino, Jose Osvaldo S.

Year:

2010

Language:

english

File:

PDF, 2.56 MB

english, 2010

33

Frequency of exceptional Nile flood events as an indicator of Holocene hydro-climatic changes in the Ethiopian Highlands

Mologni, Carlo, Revel, Marie, Blanchet, CÃ©cile, Bosch, Delphine, Develle, Anne-Lise, Orange, FranÃ§ois, Bastian, Luc, Khalidi, Lamya, Ducassou, Emmanuelle, Migeon, SÃ©bastien

Journal:

Quaternary Science Reviews

Year:

2020

File:

PDF, 5.96 MB

2020

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